Fluorofenidone, CAS [[848353-85-5]]

Product Overview

• Article Name: Fluorofenidone, CAS [[848353-85-5]]
• Biozol Catalog Number: MCE-HY-121246
• Supplier Catalog Number: HY-121246
• Alternative Catalog Number: MCE-HY-121246-100MG,MCE-HY-121246-10MG,MCE-HY-121246-10MMX1ML,MCE-HY-121246-5MG,MCE-HY-121246-50MG,MCE-HY-121246-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: AKF-PD

Product Description

Fluorofenidone (AKF-PD) is an orally active compound with anti-fibrotic, antioxidant, and anti-inflammatory pharmacological effects. Fluorofenidone downregulates the expression of ACSL4, upregulates GPX4 expression and inhibits the NF-kappaB signaling pathway to alleviate inflammation and fibrosis. Fluorofenidone ameliorates cholestasis and fibrosis by inhibiting hepatic Erk/-Egr-1 signaling and Tgfbeta1/Smad pathway in mice. Fluorofenidone demonstrates protective effects against chronic lung injury in mice. Fluorofenidone can be used for the study of chronic obstructive pulmonary disease (COPD), pulmonary interstitial fibrosis (PIF) and non-small cell lung cancer (NSCLC)[1][2][3].

Product Properties

• Molecular Weight: 203.21
• Purity: 99.78
• CAS Number: [848353-85-5]
• Formula: C12H10FNO
• Target: ERK,NF-kappaB,TGF-beta/Smad

Application Notes

• Application Notes: MCE Product type: Reference compound