Doxorubicinone (Adriamycin aglycone) is the aglycone of the antibiotic Doxorubicin (HY-15142A), i.e., its sugar-free parent nucleus structure. Doxorubicinone does not induce DNA damage or bind to RelA, but still downregulates the expression of pro-inflammatory cytokines (such as TNF, IL-12, etc.) regulated by the NF-kappaB pathway. Doxorubicinone can be used in sepsis-related research[1][2][3].
Molecular Weight:
414.36
Purity:
98.29
CAS Number:
[24385-10-2]
Formula:
C21H18O9
Target:
Drug Derivative,Interleukin Related,NF-kappaB,TNF Receptor
Application Notes:
MCE Product type: Reference compound
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