Dinactin, an antibiotic ionophore produced by Streptomyces species, as an effective small molecule targeting Wnt/beta-catenin signaling pathway in cancer cells. Dinactin shows marked inhibition of HCT-116 cell growth with an IC50 of 1.1 µM. Dinactin shows anti-proliferative activity against the cancer cells in apoptosis-independent manner. Dinactin is also an effective agent for the research of neuropathic pain[1].
Molecular Weight:
764.98
CAS Number:
[20261-85-2]
Formula:
C42H68O12
Target:
Antibiotic,Bacterial,Wnt,beta-catenin
Application Notes:
MCE Product type: Natural Products
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