Lactandrate is a D-high nitrogen steroid alkylating agent. It can interact with the ligand-binding domain (LBD) of estrogen receptor-alpha (ERalpha). Lactandrate has a growth inhibitory effect on breast cancer cells, with a GI50 value ranging from 5 to 65 µM. It shows anti-tumor activity in mouse breast tumors (MXT and CD8F1) as well as in human xenograft MX-1[1].
Molecular Weight:
563.60
CAS Number:
[43000-65-3]
Formula:
C31H44Cl2N2O3
Target:
Estrogen Receptor/ERR
Application Notes:
MCE Product type: Reference compound
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