(E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603 (IT-603). (E/Z)-IT-603 is also an IkappaBalpha/c-Rel inhibitor. IT-603 is a c-Rel inhibitor with an IC50 of 3 µM. IT-603 has anti-tumor activity. (E/Z)-IT-603 is a promising modulator of T-cell responses in the context of graft-versus-host disease (GVHD) and malignant diseases[1].
Molecular Weight:
329.17
Purity:
99.91
CAS Number:
[292168-90-2]
Formula:
C11H9BrN2O3S
Target:
NF-kappaB
Application Notes:
MCE Product type: Reference compound
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