PNU-120596 (NSC 216666) is a potent and selective alpha7 nAChR positive allosteric modulator (PMA) with an EC50 of 216 nM. PNU-120596 is inactive against alpha4beta2, alpha3beta4, and alpha9alpha10 nAChRs. PNU-120596 has the potential for psychiatric and neurological disorders research[1].
Molecular Weight:
311.72
Purity:
99.49
CAS Number:
[501925-31-1]
Formula:
C13H14ClN3O4
Target:
nAChR
Application Notes:
MCE Product type: Reference compound
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