MIND4-17 is a potent NRF2 activator that covalently modifies a C151 residue of Keap1. MIND4-17 disrupts Keap1-Nrf2 association, leading to Nrf2 protein stabilization and nuclear translocation. MIND4-17 exerts potent antioxidant activity[1][2].
Molecular Weight:
405.43
Purity:
99.05
CAS Number:
[345989-24-4]
Formula:
C20H15N5O3S
Target:
Keap1-Nrf2
Application Notes:
MCE Product type: Reference compound
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