CAY10404 is a potent and selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 1 nM and a selectivity index (SI, COX-1 IC50/COX-2 IC50) of >500000. CAY10404 is a potent PKB/Akt and MAPK signaling pathways inhibitor and induces apoptosis in non-small cell lung cancer (NSCLC) cells. CAY10404, a diarylisoxazole, has good analgesic, anti-inflammatory, and anti-cancer activities[1][2][3].
Molecular Weight:
367.34
Purity:
99.69
CAS Number:
[340267-36-9]
Formula:
C17H12F3NO3S
Target:
Akt,Apoptosis,COX
Application Notes:
MCE Product type: Reference compound1
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