IMTPPE is an inhibitor of the androgen receptor (AR) in C4-2 prostate cancer cells, inhibiting its transcriptional activity and protein levels. IMTPPE inhibited the proliferation of AR-positive prostate cancer cells but had no effect on AR-negative prostate cancer cells. IMTPPE also inhibited the growth of enzalutamide-resistant 22Rv1 xenograft tumors[1].
Molecular Weight:
373.51
CAS Number:
[851688-13-6]
Formula:
C20H27N3O2S
Target:
Adrenergic Receptor
Application Notes:
MCE Product type: Reference compound
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