INI-43 is an inhibitor of Kpnbeta1, interfering with the nuclear localization of Kpnbeta1 and known Kpnbeta1 cargo proteins, NFAT, NFkappaB, AP-1, and NFY. INI-43 can inhibit the proliferation of cancer cells, cause G2-M cell cycle arrest in cancer cells, and induce the intrinsic apoptosis pathway[1][2][3].
Molecular Weight:
385.46
Purity:
99.28
CAS Number:
[881046-01-1]
Formula:
C22H23N7
Target:
AP-1,Apoptosis
Application Notes:
MCE Product type: Reference compound1
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