alpha-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. alpha-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for alpha-Thujone is 21 µM in suppressing the GABA-induced currents. alpha-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. alpha-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and can cross the blood-brain barrier[1][2][3].
Molecular Weight:
152.24
Purity:
98.07
CAS Number:
[546-80-5]
Formula:
C10H16O
Target:
Apoptosis,Autophagy,Environmental Pollutants,GABA Receptor,Parasite,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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