Prinomastat (AG3340) is a broad spectrum, potent, orally active metalloproteinase (MMP) inhibitor with IC50s of 79, 6.3 and 5.0 nM for MMP-1, MMP-3 and MMP-9, respectively. Prinomastat inhibits MMP-2, MMP-3, MMP-13 and MMP-9 with Kis of 0.05 nM, 0.3 nM, 0.03 nM and 0.26 nM, respectively. Prinomastat crosses blood-brain barrier. Antitumor avtivity[1][2][3][4].
Molecular Weight:
423.51
Purity:
98.41
CAS Number:
[192329-42-3]
Formula:
C18H21N3O5S2
Target:
Apoptosis,MMP
Application Notes:
MCE Product type: Reference compound
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