A 65281 is a potent DNA gyrase inhibitor with an IC50 value of 0.1 µg/mL. A 65281 induces DNA breakage mediated by calf thymus topoisomerase II. A 65281 inhibits P4 DNA unknotting with an IC50 value of 8 µg/mL[1].
Molecular Weight:
378.40
CAS Number:
[111279-49-3]
Formula:
C17H16F2N4O2S
Target:
Bacterial,DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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