ONO-AE 248 is a selective EP3 receptor agonist with cardioprotective activity. ONO-AE 248 reduces myocardial infarction size by selectively binding to the EP3alpha receptor in mice. The cardioprotective effect of ONO-AE 248 is independent of hemodynamic effects. The mechanism of ONO-AE 248 may involve activation of protein kinase C and opening of K(ATP) channels[1].
Molecular Weight:
380.52
Purity:
98.27
CAS Number:
[211230-67-0]
Formula:
C22H36O5
Target:
Endogenous Metabolite,Prostaglandin Receptor
Application Notes:
MCE Product type: Reference compound
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