4-Br-Bnlm is a selective inhibitor of glucose-regulated protein 94 (Grp94) with an EC50 value of 0.96 µM. 4-Br-Bnlm reduces the levels of mutant myocilin proteins as well as wild-type myocilin misfold in cells. 4-Br-Bnlm promotes the clearance of toxic formsof myocilin and reduces myocilin toxicity[1][2].
Molecular Weight:
465.72
Purity:
99.46
CAS Number:
[1654775-71-9]
Formula:
C20H18BrClN2O4
Target:
HSP
Application Notes:
MCE Product type: Reference compound
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