Revaprazan (SB 641257) is reversible proton pump inhibitor. Revaprazan can inhibit gastric acid secretion and protect gastric mucosa. Revaprazan can inhibit IkappaB-alpha degradation as well as Akt inactivation, resulting in attenuation of H. pylori-induced COX-2 expression. Revaprazan can be used for the researches of infection and inflammmation, such as H. pylori-infected gastric inflammation and gastric ulcer[1][2].
Molecular Weight:
362.44
CAS Number:
[199463-33-7]
Formula:
C22H23FN4
Target:
Akt,Bacterial,COX,ERK,NF-kappaB,Proton Pump
Application Notes:
MCE Product type: Reference compound
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