PU3 is an Hsp90 inhibitor that competes with geldanamycin (GM) and others for the conserved ATP/ADP pocket of Hsp90. PU3 also induces degradation of proteins such as Her2 and inhibits breast cancer cell growth by causing retinoblastoma protein hypophosphorylation, G1 arrest, and cell differentiation. PU3 has the potential to be a cancer inhibitor.[1].
Molecular Weight:
371.43
CAS Number:
[352519-21-2]
Formula:
C19H25N5O3
Target:
HSP
Application Notes:
MCE Product type: Reference compound
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