APTO-253 (LOR-253) hydrochloride is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 hydrochloride mediates anticancer activity via induction of Kruppel-like factor 4 (KLF4) tumor suppressor. APTO-253 hydrochloride exhibits antiarthritic activity.
Molecular Weight:
280.32
CAS Number:
[120280-33-3]
Formula:
C17H16N2O2
Target:
Apoptosis,c-Myc
Application Notes:
MCE Product type: Reference compound
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