A-423579 is an orally active non-imidazole histamine H3 receptor antagonist. A-423579 exhibits high affinity and good selectivity for human and rat H3 receptors, and possesses both antagonistic and inverse agonistic activities. A-423579 can effectively reduce body weight in obese rodents, with concomitant decreases in fat content, plasma leptin levels, and triglycerides. A-423579 possesses anti-obesity activity and can be used in the research of obesity and related metabolic disorders[1][2].
Molecular Weight:
385.45
CAS Number:
[461045-17-0]
Formula:
C22H25F2N3O
Target:
Histamine Receptor
Application Notes:
MCE Product type: Reference compound
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