PF-05186462 is a potent and selective inhibitor of human Nav1.7 voltage-dependent sodium channel, with an IC50 of 21 nM. PF-05186462 shows significant selectivity for Nav1.7 versus other sodium channels (Nav 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, and 1.8). PF-05186462 can be used for the research of acute or chronic pain[1].
Molecular Weight:
531.89
Purity:
99.69
CAS Number:
[1235406-03-7]
Formula:
C19H10ClF4N5O3S2
Target:
Sodium Channel
Application Notes:
MCE Product type: Reference compound
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