NPD926 is a small molecule that targets glutathione and induces cancer cell death. The Xc- system and glutathione are therapeutic targets in cancer. NPD926 causes cellular glutathione depletion and subsequent generation of reactive oxygen species (ROS), thereby sensitizing fibroblasts to Xc- system inhibitors. NPD926 is a ROS inducer with anticancer activity.[1].
Molecular Weight:
479.05
CAS Number:
[384361-79-9]
Formula:
C29H35ClN2O2
Target:
Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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