JR-AB2-011, CAS [[2411853-34-2]]

Product Overview

• Article Name: JR-AB2-011, CAS [[2411853-34-2]]
• Biozol Catalog Number: MCE-HY-122022
• Supplier Catalog Number: HY-122022
• Alternative Catalog Number: MCE-HY-122022-10MG,MCE-HY-122022-5MG,MCE-HY-122022-50MG,MCE-HY-122022-25MG,MCE-HY-122022-100MG,MCE-HY-122022-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

JR-AB2-011 is a selective mTORC2 inhibitor with an IC50 value of 0.36 µM. JR-AB2-011 inhibits mTORC2 activity by blocking Rictor-mTOR association (Ki: 0.19 µM)[1].JR-AB2-011 decreases the phosphorylation level of Akt, decreases MMP2 activity, thereby reducing the ability of tumor cells to migrate and invade. JR-AB2-011 also induces non-apoptotic cell death[2].

Product Properties

• Molecular Weight: 398.28
• Purity: 98.15
• CAS Number: [2411853-34-2]
• Formula: C17H14Cl2FN3OS
• Target: mTOR

Application Notes

• Application Notes: MCE Product type: Reference compound