TBC3486 is a highly selective integrin alpha4beta1 inhibitor. TBC3486 acts as a chemosensitizer to enhance the sensitivity of leukemia cells to chemotherapy. TBC3486 exhibits efficacy in preclinical models of integrin alpha4-dependent inflammatory and autoimmune diseases, including a mouse model of autoimmune encephalomyelitis. TBC3486 can be used for the research of precursor B-cell acute lymphoblastic leukemia[1].
Molecular Weight:
557.68
CAS Number:
[247044-77-5]
Formula:
C27H31N3O6S2
Target:
Integrin
Application Notes:
MCE Product type: Reference compound
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