PFK-015, a derivative of 3PO, is a specific PFKFB3 inhibitor. PFK-015 inhibits recombinant PFKFB3 with an IC50 value of 110 nM and inhibits PFKFB3 activity in cancer cells with an IC50 value of 20 nM. PFK-015 can be used for the research of multiple cancers such as lung cancer, stomach cancer, colon cancer and esophageal squamous cell carcinoma (ESCC)[1][2].
Molecular Weight:
260.29
Purity:
99.80
CAS Number:
[4382-63-2]
Formula:
C17H12N2O
Target:
Autophagy
Application Notes:
MCE Product type: Reference compound
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