SW063058 is an autophagy inducer that specifically disrupts the binding of Beclin 1 to Bcl-2 while leaving the interaction between Bcl-2 and pro-apoptotic members like Bax and BIM unaffected. By inhibiting the negative regulatory effects of Bcl-2 on Beclin 1, which is crucial for the initiation of autophagy, SW063058 promotes autophagic activity without triggering cytotoxicity, apoptosis, or other forms of cell death in vitro.
Molecular Weight:
565.17
CAS Number:
[533876-30-1]
Formula:
C22H15BrFIN2O2
Target:
Autophagy
Application Notes:
MCE Product type: Reference compound
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