FR260330 is a selective, orally active inhibitor for inducible nitric oxide synthase (iNOS) through suppression of iNOS dimerization. FR260330 inhibits the NO accumulation in rat splenocytes and human DLD-110 cells, with IC50 of 27 and 10 nM. FR260330 ameliorates the Lipopolysaccharides (HY-D1056)-induced inflammatory diseases in rats model[1].
Molecular Weight:
617.02
CAS Number:
[442198-67-6]
Formula:
C29H28ClF3N6O4
Target:
NO Synthase
Application Notes:
MCE Product type: Reference compound
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