CPI-644 is a selective EP300/CBP bromodomain inhibitor, with an IC50 of 0.18 µM against the CBP bromodomain. CPI-644 reduces the proportion of FOXP3+ cells and downregulates the expression of LAG-3, CTLA-4 and PD-1. CPI-644 can be used in cancer-related research[1].
Molecular Weight:
357.43
CAS Number:
[1904647-34-2]
Formula:
C18H19N3O3S
Target:
CTLA-4,Histone Acetyltransferase,LAG-3,PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound
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