NVP-2 is a potent and selective ATP-competitive cyclin dependent kinase 9 (CDK9) probe, inhibits CDK9/CycT activity with an IC50 of 0.514 nM. NVP-2 displays inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases with IC50 values of 0.584 µM, 0.706 µM, and 0.605 µM, respectively. NVP-2 induces cell apoptosis.[1]
Molecular Weight:
513.07
Purity:
99.29
CAS Number:
[1263373-43-8]
Formula:
C27H37ClN6O2
Target:
Apoptosis,CDK
Application Notes:
MCE Product type: Reference compound
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