IMB-301 is a specific HIV-1 replication inhibitor that binds to hA3G (human APOBEC3G), interrupts the hA3G-Vif interaction and inhibits Vif-mediated degradation of hA3G. IMB-301 inhibits the replication of HIV-1 in H9 cells (IC50=8.63 uM). Human APOBEC3G is a restriction factor that inhibits human immunodeficiency 1 virus (HIV-1) replication[1].
Molecular Weight:
379.26
Purity:
99.08
CAS Number:
[64009-84-3]
Formula:
C19H17Cl2FN2O
Target:
HIV
Application Notes:
MCE Product type: Reference compound
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