UMK57, CAS [[342595-74-8]]

Product Overview

• Article Name: UMK57, CAS [[342595-74-8]]
• Biozol Catalog Number: MCE-HY-122236
• Supplier Catalog Number: HY-122236
• Alternative Catalog Number: MCE-HY-122236-10MG,MCE-HY-122236-25MG,MCE-HY-122236-50MG,MCE-HY-122236-100MG,MCE-HY-122236-5MG,MCE-HY-122236-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

UMK57 is a MCAK activator and kinetochore-microtubule destabilizer. UMK57 enhances MCAK-dependent microtubule depolymerization, increases kinetochore-microtubule turnover, reduces chromosome mis-segregation and lagging chromosomes, and inhibits cancer cell proliferation. UMK57 triggers adaptive resistance in Aurora B cancer cells via reversible Aurora B signaling pathway alterations. UMK57 can be used for the research of solid tumors[1][2].

Product Properties

• Molecular Weight: 295.40
• Purity: 99.51
• CAS Number: [342595-74-8]
• Formula: C17H17N3S
• Target: Aurora Kinase,Kinesin,Microtubule/Tubulin,Mitosis

Application Notes

• Application Notes: MCE Product type: Reference compound