Orvepitant (GW823296) is potent, selective, orally active and well-tolerated neurokinin-1 receptor (NK-1) antagonist with a pKi of 10.2 for human neurokinin-1 receptor. Orvepitant can across the blood-brain barrier. Orvepitant has the potential for depressive disorder and chronic refractory cough (CRC) treatment[1][2].
Molecular Weight:
628.62
CAS Number:
[579475-18-6]
Formula:
C31H35F7N4O2
Target:
Neurokinin Receptor
Application Notes:
MCE Product type: Reference compound
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