OSU-03013 is a Celecoxib (HY-14398) analog. OSU-03013 can promote apoptosis, up-regulate E-cadherin, and down-regulate beta-catenin, c-myc, Wnt1, and N-cadherin. OSU-03013 reduces cell migration and invasion. OSU-03013 regulates both Wnt and mTOR expression to inhibit colon cancer (CC) cell proliferation. OSU-03013 can be used for CC cancer research[1].
Molecular Weight:
445.44
CAS Number:
[742112-34-1]
Formula:
C25H18F3N5
Target:
Apoptosis,Cadherin,c-Myc,mTOR,Wnt,beta-catenin
Application Notes:
MCE Product type: Reference compound
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