rel-Levormeloxifene (rel-L-Centchroman) is the relative configuration of Levormeloxifene (HY-122359). rel-Levormeloxifene is a selective estrogen receptor modulator (SERM). rel-Levormeloxifene inhibits proliferation of leukemia cells with IC50 about 7 µM, arrests cell cycle at G0/G1 phase, and induces apoptosis. rel-Levormeloxifene induces differentation of myelogenesis leukemia, and enhances ROS production in K562 cells[1].
Molecular Weight:
457.60
CAS Number:
[31477-60-8]
Formula:
C30H35NO3
Target:
Apoptosis,Estrogen Receptor/ERR,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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