GBR 12935 dihydrochloride is a potent, and selective dopamine reuptake inhibitor, with the binding constant (Kd) of 1.08 nM in COS-7 cells. GBR 12935 dihydrochloride stimulates the locomotion activity in different mice strains but fails to induce stereotypy. Thus, GBR 12935 dihydrochloride also prevents the d-Fenfluramine-induced head-twitch response in mice[1][2][3][4].
Molecular Weight:
487.50
Purity:
99.80
CAS Number:
[67469-81-2]
Formula:
C28H36Cl2N2O
Target:
Dopamine Transporter
Application Notes:
MCE Product type: Reference compound1
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