PPACK dihydrochloride is a potent and selective irreversible thrombin inhibitor. PPACK dihydrochloride serves as an alternative anticoagulant to lithium heparin (LiHep) for blood gas and whole blood electrolyte analyses. PPACK dihydrochloride also acts as an inhibitor of plasminogen activator (rt-PA). PPACK dihydrochloride inhibits the binding of rt-PA to plasma protease inhibitors. PPACK dihydrochloride attenuates the plasmin-induced increase in endothelial permeability and endothelial morphological changes in bovine aortic endothelial cell monolayers, and can be used in thrombosis-related research[1][2][3].
Molecular Weight:
523.88
Purity:
99.07
CAS Number:
[82188-90-7]
Formula:
C21H33Cl3N6O3
Target:
PAI-1,Thrombin
Application Notes:
MCE Product type: Peptides
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