AVG-233 is a potent, orally active RNA dependent RNA polymerase (RdRp) inhibitor. AVG-233 prevents initiation of the viral polymerase complex at the promoter. AVG-233 binding site is present in the L1-1749 fragment. AVG-233 has nanomolar activity against both RSV strains and clinical RSV isolates (EC50=0.14-0.31 µM). AVG-233 can be used for research of respiratory syncytial virus (RSV)[1][2].
Molecular Weight:
487.94
Purity:
98.87
CAS Number:
[2151937-80-1]
Formula:
C26H22ClN5O3
Target:
DNA/RNA Synthesis,RSV
Application Notes:
MCE Product type: Reference compound
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