T-5224-d8 is the deuterium labeled T-5224 (HY-12270). T-5224 is a transcription factor c-Fos/activator protein (AP)-1 inhibitor with anti-inflammatory effects, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors. T-5224 inhibits the IL-1beta-induced up-regulation of Mmp-3, Mmp-13 and Adamts-5 transcription[1][2].
Molecular Weight:
525.58
Formula:
C29H19D8NO8
Target:
AP-1,Isotope-Labeled Compounds,MMP
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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