GOT1 inhibitor-1 (compound 2c), a tryptamine-based derivative, acts as a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM. GOT1 plays an important role in energy metabolism and Reactive Oxygen Species (ROS) balance. GOT1 inhibitor-1 can be used for the research of pancreatic ductal adenocarcinoma (PDAC)[1].
Molecular Weight:
354.83
Purity:
98.75
CAS Number:
[732973-87-4]
Formula:
C19H19ClN4O
Target:
Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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