Umbralisib (TGR-1202) hydrochloride is an orally active, potent and selective dual PI3Kdelta and casein kinase-1-epsilon (CK1epsilon) inhibitor, with EC50 of 22.2 nM and 6.0 µM, respectively. Umbralisib hydrochloride exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib hydrochloride can be used for haematological malignancies reseach[1][2][3][4].
Molecular Weight:
608.01
Purity:
99.04
CAS Number:
[1532533-78-0]
Formula:
C31H25ClF3N5O3
Target:
Casein Kinase,PI3K
Application Notes:
MCE Product type: Reference compound
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