HLY78, a Lycorine (HY-N0288) derivative, is a potent activator of the Wnt/beta-catenin signaling pathway. HLY78 targets the DIX domain of Axin and promotes the Axin-LRP6 (lipoprotein receptor-related protein 6) association, thus promoting LRP6 phosphorylation and Wnt signal transduction. HLY78 can be used for subarachnoid hemorrhage (SAH) research[1][2][3].
Molecular Weight:
267.32
Purity:
98.44
CAS Number:
[854847-61-3]
Formula:
C17H17NO2
Target:
Apoptosis,Wnt,beta-catenin
Application Notes:
MCE Product type: Reference compound1
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