ZT-12-037-01 is a STK19-targeted inhibitor, has a high-affinity interaction with STK19 protein and inhibits oncogenic NRAS-driven melanocyte malignant transformation. ZT-12-037-01 is an ATP-competitive inhibitor, inhibiting phosphorylation of NRAS (major isoform of Ras family) with an IC50 of 24 nM[1].
Molecular Weight:
385.50
Purity:
98.06
CAS Number:
[2328073-61-4]
Formula:
C21H31N5O2
Target:
Ras,Ser/Thr Kinase
Application Notes:
MCE Product type: Reference compound
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