YH239-EE, CAS [[1364488-67-4]]

Product Overview

• Article Name: YH239-EE, CAS [[1364488-67-4]]
• Biozol Catalog Number: MCE-HY-12287
• Supplier Catalog Number: HY-12287
• Alternative Catalog Number: MCE-HY-12287-5MG,MCE-HY-12287-10MG,MCE-HY-12287-50MG,MCE-HY-12287-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

YH239-EE, ethyl ester of the free carboxylic acid compound YH239, is a potent p53-MDM2 antagonizing and apoptosis-inducing agent. IC50 value: Target: MDM2/p53 YH239-EE inhibits the growth of OCI-AML-3 cells with wild type p53 by inhibiting the p53-MDM2 interaction. YH239-EE induces cell cycle arrest and causes potent cell apoptosis via activation of p53 and downstream targets in four AML cells (OCI-AML-3 and MOLM-13 with wt p53, NB4 with p53 mutation, and HL60 with p53 deletion).

Product Properties

• Molecular Weight: 504.41
• Purity: 98.28
• CAS Number: [1364488-67-4]
• Formula: C25H27Cl2N3O4
• Target: Apoptosis,E1/E2/E3 Enzyme,MDM-2/p53

Application Notes

• Application Notes: MCE Product type: Reference compound