Tanshindiol C is a S-adenosylmethionine-competitive EZH2 (Histone Methyltransferase) inhibitor with an IC50 of 0.55 µM for inhibiting the methyltransferase activity. Tanshindiol C is also an activator of both Nrf2 and Sirtuin 1 (Sirt1) in macrophages. Tanshindiol C possesses anti-cancer activity, and can be used for atherosclerosis research[1][2].
Molecular Weight:
312.32
Purity:
98.47
CAS Number:
[97465-71-9]
Formula:
C18H16O5
Target:
Histone Methyltransferase,Keap1-Nrf2,Sirtuin
Application Notes:
MCE Product type: Reference compound
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