Navtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC50 of 0.6 nM. Navtemadlin binds to MDM2 with a Kd of 0.045 nM[1][2].
Molecular Weight:
568.55
Purity:
99.61
CAS Number:
[1352066-68-2]
Formula:
C28H35Cl2NO5S
Target:
E1/E2/E3 Enzyme,MDM-2/p53
Application Notes:
Reference compound
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