BTSA1 is a potent, high affinity and orally active BAX activator with an IC50 of 250 nM and an EC50 of 144 nM. BTSA1 binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis[1].
Molecular Weight:
430.51
Purity:
99.77
CAS Number:
[314761-14-3]
Formula:
C21H14N6OS2
Target:
Apoptosis,Bcl-2 Family
Application Notes:
Reference compound
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