(-)-Indolactam V is a PKC activator, with Kis of 3.36 nM, 1.03 µM for eta-CRD2 (PKCeta surrogate peptide), gamma-CRD2 (PKCgamma surrogate peptide), and Kds of 5.5 nM (eta-C1B), 7.7 nM (epsilon-C1B), 8.3 nM (delta-C1B), 18.9 nM (beta-C1A-long), 20.8 nM (alpha-C1A-long), 137 nM (beta-C1B), 138 nM (gamma-C1A), 213 nM (gamma-C1B), and has antitumor activity.
Molecular Weight:
301.38
Purity:
98.75
CAS Number:
[90365-57-4]
Formula:
C17H23N3O2
Target:
PKC
Application Notes:
Reference compound
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