MS-1020 is a potent and ATP-competitive JAK3 inhibitor. MS-1020 inhibits JAK3/STAT signaling and induces apoptosis. MS-1020 promotes cell death. MS-1020 decreases the expression of tyrosine phosphorylated STAT3 levels. MS-1020 has the potential for the research of cancers harboring aberrant JAK3 signaling[1].
Molecular Weight:
346.38
CAS Number:
[1255516-86-9]
Formula:
C21H18N2O3
Target:
JAK
Application Notes:
Reference compound
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