IMB-808 is a potent LXRalpha/beta dual agonist with EC50 values of 0.53 µM and 0.15 µM (0.15 µM, using GAL4-pGL4-luc reporter plasmid) for LXRbeta and LXRalpha, respectively. IMB-808 promotes expression of genes related to reverse cholesterol transport (ABCA1 and ABCG1). IMB-808 can be used for the study of atherosclerosis research[1].
Molecular Weight:
380.32
Purity:
99.84
CAS Number:
[870768-70-0]
Formula:
C18H15F3N2O4
Target:
LXR
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted