SIRT2/6-IN-1 (Compound 5) is a SIRT6/SIRT2 inhibitor, with IC50s of 106 µM and 114 µM. SIRT2/6-IN-1 increases H3K9 acetylation, increases glucose uptake and reduces TNF-alpha secretion in cells[1].
Molecular Weight:
410.40
Purity:
99.79
CAS Number:
[1214468-35-5]
Formula:
C19H14N4O5S
Target:
Histone Demethylase,Sirtuin
Application Notes:
MCE Product type: Reference compound
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