GSK2194069 is a potent inhibitor of beta-ketoyl reductase (KR) of fatty acid synthase (FASN), with an IC50 value of 7.7 nM. GSK2194069 shows specifically inhibitory effect on FAS expressing cancer cells, by acting potent efficacy on acetoacetyl-CoA, NADPH with IC50 or Ki values of 4.8 nM and 5.6 nM, respectively[1][2][3].
Molecular Weight:
428.48
Purity:
99.80
CAS Number:
[1332331-08-4]
Formula:
C25H24N4O3
Target:
Fatty Acid Synthase (FASN)
Application Notes:
MCE Product type: Reference compound
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